Scientists at Feinberg are reshaping scientific understanding of the cell's tiniest components—structures once thought to be static, now revealed to be dynamic engines of cellular life. As they probe ...

Dysfunctions of the tiny cell processes (primary cilia) of the pancreatic beta cells could be a cause of type 2 diabetes. Little is known about the structure and function of these cilia. An ...

Biomedical research typically follows a familiar path: developing treatments that block, enhance or mutate certain signaling pathways, genes or proteins to change the function of different cells in ...

Researchers have profiled the molecular structure and features of a key part of the deadly Nipah virus. Experiments in cells showe how changes in the viral polymerase -- a protein involved in viral ...

In the earliest stages of life, mammalian embryos start as a disorganized cluster of cells. As development progresses, these cells become organized into well-defined shapes and structures. This ...

The design of synthetic developmental programs for multicellular mammalian systems is a cornerstone of synthetic biology. The programs hinge on the construction of gene regulatory circuits that ...

A framework for analyzing single-cell genomics data, in which geometrical properties are harnessed to obtain insights on cellular diversity, including precise clustering, clear visualizations, and ...