It was recently suggested that most miRNA genes originate from independent transcription units 9,10,11. However, about a quarter of human miRNA genes are located in introns of pre-mRNAs. Because these ...
miRNAs are ~22-nt RNAs that play a major part in the regulation of gene expression in most eukaryotic species. In humans, miRNAs are thought to post-transcriptionally repress at least 60% of mRNAs by ...
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